Raman Microscope SENTERRA II

  • Description
  • Features
  • Applications


The SENTERRA II is a confocal Raman microscope designed for straightforward, non-stop operation. Its high degree of automation allows fast and easy Raman imaging for failure analysis, quality control and scientific research.

Automation is the SENTERRA II’s key feature. It allows the user to concentrate on the essential things: the analytical problem, the Raman measurement and more importantly, the results.

SENTERRA II provides:

  • Smooth user experience
  • Research-grade performance
  • Superb wavenumber precision
  • Self-diagnosis and automated OQ/PQ
  • Virtually maintenance-free operation
  • 100% GMP & 21 CFR p11 compliance

Reproducibility, Precision and User-Safety in Raman Microscopy

The SENTERRA II is fully automated including self-diagnosis and instrument tests like OQ and PQ. Change a laser by a simple mouse-click and afterwards, filter and grating are adjusted automatically.

To use this automation to its full extent, Bruker rethought calibration and created the patented SureCalTM technology. It continuously recalibrates the device and allows permanent sub-wavenumber precision.

It’s about user safety – especially when beginners or students are involved. A class 1 laser housing and interlock always protects the user of any harmful laser radiation


SENTERRA II technical features:

  • Fully automated hardware
  • One-click switching of 4 built-in lasers
  • SureCalTM calibration technology
  • Fast 3D Raman imaging
  • Automate your own workflows in minutes
  • Powerful analysis and identification tools
  • FT-Raman for minimized fluorescence in
  • combination with FTIR instrumentation

SureCal Continuous Raman Calibration Technology 

Naturally, the SENTERRA II offers excellent sensitivity combined with pristine spectral and Raman Imaging performance. But the real powerhouse of this confocal Raman microscope is our SureCalTM technology.

Let us briefly repeat one of the most important principles of Raman technology: External factors affect the optical and mechanical components in every Raman microscope, especially heat, component changes and vibrations. Ultimately, this induces wavenumber shifts, which must be compensated by regular recalibrations.

Thanks to SureCalTM, the SENTERRA II is the only Raman microscope that is always calibrated. Don’t waste your valuable time with recalibration – start analyzing. No matter if it is a quick material identification or the collection of large data sets for PCA or other statistical methods.


Conservation and restoration of works of art

Historical works of art are extremely valuable, and preserving a part of human history is an exciting endeavor. SENTERRA II is used for the restoration of historic paintings, buildings and works of art. It offers additional tools such as Raman probes that can be used to analyze larger paintings.


From the examination of potentially forged art objects to paint analysis in forensic laboratories. Raman microscopy provides precise information about the chemical identity and origin of unknown substances. With high spatial resolution down to the nanometer range, even the smallest secrets are uncovered.

Pharmaceutical industry

At the outset, Bruker decided to respond to the needs of pharmaceutical companies. Accordingly, SENTERRA II and OPUS are fully compliant with GMP requirements, all major pharmacopeias, 21 CFR Part 11, and the ALCOA + principle. SENTERRA II ensures the integrity and security of data whether it is stored locally or on a server.

Polymers and plastics

Polymers are indispensable in everyday life, and Raman microscopy can provide key information on quality control and development of plastic products. While Raman imaging provides information regarding material distribution, dedicated spectrum libraries allow the identification of unknown materials and fillers.

Materials engineering

Whether it’s battery research or the study of graphene or silicon, Raman microscopy is widely used in materials engineering . SENTERRA II supports researchers with the highest precision and offers up to three excitation lasers, as well as optional coupling with FT-Raman to minimize fluorescence.

Environmental studies

One of the many environmental applications is microplastic analysis. Again, the high spatial resolution of Raman microscopy offers significant advantages for the analysis of the smallest microplastic (MP) particles. Automatic particle identification procedures enable fast and reliable analysis of MP contaminants.